Ventipulmin (Clenbuterol Syrup) 0,025 mg/ml 355 ml Boehringer Ingelheim

Ventipulmin (Clenbuterol Syrup) 0,025 mg/ml 355 ml Boehringer Ingelheim

Description

Information about the drug

Clenbuterol, the active ingredient in Ventipulmin®, is a sympathomimetic amine and has been the subject of intensive research in both man and domestic animals. Due to its chemical structure, a high degree of selectivity for the beta-2 receptor sites in the body has been achieved providing intense bronchodilating properties with minimum effect on the cardiovascular system.

Other properties attributed to Ventipulmin® include excellent absorption from the gastrointestinal tract following oral administration so that the oral and parenteral dose rates are identical to 0.8 mcg per kg body weight.

The duration of effects is long-lasting and in the range of 6-8 hours after a single application. Once a plateau line has been reached after 3-5 days, twice daily administration by the oral route has been found to give a satisfactory level of medication.

Clinical Experience: In clinical trials, the effects of Ventipulmin® on pulmonary function and clinical response were assessed in horses suffering from a variety of respiratory conditions including chronic obstructive pulmonary disease (COPD).
The horses responded with a marked decrease in intrathoracic pressure, a decrease in respiratory rate, and an initial decrease followed by an increase in arterial oxygen partial pressure and clinical improvement. The duration of action of a single application was 6-8 hours.
Other results showed a significant reduction in resistance to airflow and clinical improvement of the animals’ respiratory patterns.

There were no significant side effects due to the treatment in any of the clinical trials.

Treatment of respiratory disease in horses where it is considered that airway obstruction is due to bronchospasm.

Dosage and Administration
Twice daily administration of 0.8 mcg of clenbuterol per kg body weight. This is equivalent to one stroke (4 mL) of the metered dosing pump (provided with each package) for each 125 kg (275 lbs.) b.w. twice daily on the grain portion of the feed.
Route of Administration: Oral

Duration of Action: Approximately 8 hours after a single dose, 12 hours on repeated twice daily dosing.

Contraindications
Due to a potential risk of increasing the peripheral vasodilating effect of clenbuterol, it is not recommended that corticosteroids be used in conjunction with Ventipulmin®. Ventipulmin® antagonizes the effects of prostaglandin F2α and oxytocin. The action of Ventipulmin® is antagonized by β-adrenergic blocking agents.

Ventipulmin Syrup Caution
If used during pregnancy, Ventipulmin® must be discontinued at the expected time of delivery, since uterine contractions may be abolished under its influence. The effect on the fertility of breeding stallions has not been determined.

Warning
Federal law prohibits the administration of this preparation to animals that produce food or that are intended for consumption as food.
Storage
Do not store above 25°C. Protect from light.
Ventipulmin® is a registered trademark of Boehringer Ingelheim Vetmedica GmbH, used under license.

Boehringer Ingelheim (Canada) Ltd., 5180 South Service Rood, Burlington, Ontario L7L 5H4